Prostaglandin-Based Renal Protection Against Contrast-Induced Acute Kidney Injury
نویسندگان
چکیده
منابع مشابه
Prostaglandin-based renal protection against contrast-induced acute kidney injury.
It has been known for 3 decades that the kidneys rely considerably on a group of prostaglandins that are locally produced in both a constitutive and inducible fashion, primarily in the medulla, to regulate renal blood flow and a variety of functions in tubular cells that occupy that region of the kidney. Arachidonic acid released from phospholipids is converted by cyclooxygenase (COX-1 constitu...
متن کاملContrast-induced acute kidney injury.
Case Presentation: A 63-year-old man with prior mitral valve repair, hyperlipidemia, hypertension, and mild chronic renal insufficiency (creatinine 1 year earlier, 1.2 mg/dL) presents to the emergency department with progressive dyspnea on exertion and new anterior T-wave inversions. Subsequent laboratory testing confirms a myocardial infarction (troponin I, 11.0 ng/mL) and worsening renal insu...
متن کاملContrast-induced Acute Kidney Injury
• Objective: To review the risk factors, definition, pathophysiology, prevention, and adverse outcomes associated with the development of acute kidney injury resulting from iodinated contrast. • Methods: Case presentation and evaluation of the
متن کاملContrast-induced acute kidney injury.
Cardiac angiography and coronary/vascular interventions depend on iodinated contrast media and consequently pose the risk of contrast-induced acute kidney injury (AKI). This is an important complication that accounts for a significant number of cases of hospital-acquired renal failure, with adverse effects on prognosis and health care costs. The epidemiology and pathogenesis of contrast-induced...
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REPLY: Vitamin E May Protect Against Contrast-Induced Acute Kidney Injury McCullough et al. (1) reviewed the pathophysiology and treatment options for contrast-induced acute kidney injury (CI-AKI). They stated that no effective adjunctive pharmaceutical had been demonstrated that either prevented or treated CI-AKI. However, they also suggested that of the agents being investigated, statins were...
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ژورنال
عنوان ژورنال: Circulation
سال: 2009
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.109.902189